T-cells and Immune Regulation
![Sansom, David Sansom, David](https://www.ucl.ac.uk/inflammation-tissue-repair-fibrosis/sites/inflammation_tissue_repair_fibrosis/files/styles/non_responsive/public/Sansom.png?itok=adLp1b_l)
David Sansom is Professor and Chair in Transplant Immunology at UCL Institute of Immunity and Transplantation.
His major research interests involve investigating fundamental aspects of how T cells determine whether to make immune responses or not. In particular focusing on the interplay between two receptors on T cells, CD28 and CTLA-4 and their binding partners, CD80 and CD86. His lab's work on the underlying molecular and cellular mechanisms has led to advances in understanding how the CD28/CTLA-4 system functions and this knowledge has been used to develop tests of human T cell function and regulatory T cell suppression.
Visit David Sansom's IRIS Profile >
Email address: d.sansom@ucl.ac.uk