Medicine Case & Seminar Series 2023-24

Our UCL Medicine Case and Seminar Series is on Tuesdays 1pm-2pm in the Rayne Second Floor Seminar Room / Royal Free Hospital, with lunch provided. Presentations are led by Principal Investigators.

Autumn 2023

Date	Coordinator	On-site facilitator	Medicine Case	Science Seminar	Location	Remote facilitator
12 Sept 2023	Derek Gilroy, ETM	Alison Kelly	A New Climate. Why we need to act, and what we need to do Prof. Hugh Montgomery		Rayne	Winnie Han Langner, Kate Henderson, Royal Free (ILDH Seminar Room)
19 Sept 2023	Rachel Chambers / Jeremy Brown, Respiratory	Nicole Halliday	Targeting antimicrobial resistant Acinetobacter baumannii infections Prof. Jeremy Brown		Rayne	Lynn Knight, Alison Kelly, Royal Free
26 Sept 2023	Krista Rombouts, ILDH	Alison Kelly	Combating the rising tide of cirrhosis re-admissions: the role of digital therapeutics Prof. Raj Mookerjee		Royal Free, ILDH Seminar Room	Esther Geary, Rayne
03 Oct 2023	Alan Salama, Renal	Kate Henderson / Winnie Han Langner	A green and pleasant land: bucolic countryside, deadly poisons and ultrarare disease Dr Stephen (Ben) Walsh		Royal Free, ILDH Seminar Room	Co-host, Prof. Sam Janes AV: Alison Kelly, Rayne
10 Oct 2023	Derek Gilroy, ETM	Alison Kelly	Sudden cardiac death: from challenging the coroner's autopsy to finding a therapeutic solution Prof. John Martin & Prof. Dave Selwood		Rayne	Co-host, Dr Adrian Brown AV: Winnie Han Langner, Royal Free
17 Oct 2023	David Abraham, Inflammation	Korsa Khan	Antibody-associated reversal of transthyretin amyloid cardiomyopathy Prof. Julian Gillmore	Pathophysiology and mechanisms of transthyretin aggregation Dr Guglielmo Verona	Royal Free, ILDH Seminar Room	Co-host, Coziana Ciurtin AV: Alison Kelly, Rayne
31 Oct 2023	Dave Selwood, WIBR	Andrea Goncalves	Neural mechanisms causing acute and chronic pain in humans Prof. Martin Koltzenburg, Clinical & Movement Neurosciences	Cortical processing of persistent pain Dr Liam Browne	Rayne	AV: Winnie Han Langner, Kate Henderson, Royal Free
07 Nov 2023	Steve Halligan, Imaging	Alison Kelly	A GBA1 variant carrier with agitated dreams and a hoarse voice Dr Marco Toffoli	Glymphatic clearance of alpha-synuclein: a novel therapeutic target in Parkinson's? Dr Ian Harrison	Rayne	AV: Lynn Knight, Royal Free
14 Nov 2023	Rachel Chambers / Jeremy Brown, Respiratory	Nicole Halliday	Tuberculosis: still crazy after all these years Prof. Marc Lipman	Making an IMPACT on adherence to treatment for TB Prof. Marc Lipman	Royal Free, ILDH Seminar Room	AV: Alison Kelly / Nicole Halliday
21 Nov 2023	Krista Rombouts, ILDH	Lynn Knight	Infection and cirrhosis: a decade & 2.5 multi-centre clinical trials -but any answers! Prof. Alistair O'Brien		Royal Free, ILDH Seminar Room	Alison Kelly, Rayne
28 Nov 2023	Alan Salama, Renal	Kate Henderson / Winnie Han Langner	Immunsing the immunosuppressed transplant patients Prof. Alan Salama	Rethinking urinary tract infection as one black-and-white disease - a journey into the grey areas Prof. Jennifer Rohn	Host: Rhys Evans AV: Kate Henderson	Host: Puja Mehta AV: Alison Kelly
05 Dec 2023	Derek Gilroy, ETM	Alison Kelly	Early Diagnosis of Lung Cancer - Cases from the SUMMIT and ASCENT Trials Dr Ruth Prendecki	Harnessing emerging digital and quantum technologies for early disease diagnosis Prof. Rachel McKendry, London Centre for Nanotechnology	Rayne	Host: John Hurst AV: Lynn Knight, Royal Free
12 Dec 2023	David Abraham, Inflammation	Esther Geary / Jeannie Berkeley	Too young for this! Cardiovascular risk in childhood-onset lupus Prof. Coziana Ciurtin		Rayne Host: Lizzy Rosser AV: Alison Kelly	Royal Free, IDLH Seminar Room Host: Markella Ponticos AV: Millie Williams / Lynn Knight

Spring 2024

Date	Coordinator	On-site facilitator	Medicine Case	Science Seminar	Location	Remote facilitator
16 Jan 2024	Derek Gilroy, ETM	Alison Kelly	Antibiotics in sepsis: a SWOT analysis - changing perspectives and novel approaches Prof. Mervyn Singer & Dr Nishkantha Arulkumaran		Rayne Host: Derek Gilroy AV: Alison Kelly	Royal Free Host: David Abraham AV: Lynn Knight
23 Jan 2024	Rachel Chambers / Jeremy Brown, Respiratory	Nicole Halliday	The role of APOBEC3B in lung tumour evolution and targeted cancer therapy resistance Dr Debbie Caswell		Rayne Host: Rachel Chambers AV: Alison Kelly / Catriona Heredia	Royal Free Host: Marc Lipman AV: Millie Williams / Jeannie Berkeley
30 Jan 2024	Dave Selwood, WIBR		Adaptive myelination: Re-shaping neural circuits Dr Matthew Swire, WIBR	*Cognitive decline as a trigger event to establish disease activity and treatment escalation in RMS* Professor Klaus Schmierer Professor of Neurology, Queen Mary's University	Rayne Host: Derek Gilroy AV: Alison Kelly	Royal Free Host: Markella Ponticos AV: Lynn Knight
06 Feb 2024	Alan Salama, Renal	Kate Henderson / Winnie Han Langner	Using RaDaR to fight kidney failure Prof. Daniel Gale		Royal Free Host: Rhys Evans AV: Kate Henderson	Rayne Host: Ramon Garcia Maset AV: Alison Kelly
20 Feb 2024	Derek Gilroy, ETM	Alison Kelly	Harnessing science to cure diseases Prof. Derek Gilroy & Prof. Debajit Sen		Rayne Host: Dr Olivia Bracken AV: Alison Kelly / Cat/ Esther	Royal Free Host: Guglielmo Verona AV: Kate Henderson
27 Feb 2024	David Abraham, Inflammation	Esther Geary / Jeannie Berkeley	'Decoding clinical, molecular and cellular diversity in systemic sclerosis' Prof. Chris Denton and Dr Kristina Clark		Royal Free, ILDH Seminar Room Host: Dr Voon Ong AV: Millie Williams	Rayne Host: Coziana Ciurtin AV: Esther Geary/Alison Kelly
05 Mar 2024	Dave Selwood, WIBR		'Inhibitory neurons of the cerebral cortex: from development to disease' Professor Dimitri Kullmann Professor of Neurology & Professor Nicoletta Kessaris Professor of Neuroscience		Rayne Host: David Selwood AV: Andrea Goncalves & Alison Kelly	Royal Free Host: Jill Norman AV: Lynn Knight
12 Mar 2024	David Abraham, Inflammation	Alison Kelly	'Targeting CD206 positive macrophages to treat inflammatory fibrosis' Richard Stratton and Sandra Lopez Centre for Rheumatology UCL Division of Medicine		Rayne Host: Derek Gilroy AV: Alison Kelly	Royal Free Host: David Abraham AV: Jeannie Berkeley
19 Mar 2024	Rachel Chambers / Jeremy Brown, Respiratory	Catriona Heredia	Division of Medicine Social Event - teas and coffees

Summer 2024

Date	Coordinator	On-site facilitator	Medicine Case	Science Seminar	Location	Remote facilitator
09 Apr 2024	Krista Rombouts, IDLH	Lynn Knight	'Acute on Chronic Liver Failure' Prof. Rajiv Jalan		Royal Free Host: Krista Rombouts AV: Lynn Knight	Rayne Host: Derek Gilroy AV: Alison Kelly
16 Apr 2024	Alan Salama, Renal	Kate Henderson / Winnie Han Langner	'Autosomal Dominant Polycystic Kidney Disease (ADPKD): Mechanisms, models and potential therapies' Professor Jill Norman & Professor Patricia Wilson UCL Centre for Kidney and Bladder Health		Royal Free Host:Dr Keith Siew AV: Kate Henderson	Rayne Host: Dr Manu Platé AV: Alison Kelly
23 Apr 2024	Derek Gilroy, ETM	Alison Kelly	“Ultra-processed Food: misinformation or the missing piece” Science Seminar: Dr Adrian Brown & Sam Dicken UCL Centre for Obesity Research Medicine Case: Dr Chris van Tulleken UCLH and The Hospital for Tropical Diseases BBC TV Presenter This seminar will cover Chris Van Tulleken's personal experience and results of following a UPF diet for a BBC documentary, which helped in the development of the Centre’s recent randomised trial UPDATE investigating the impact of a UPF diet meeting UK dietary guidance on health.		Rayne Host: Derek Gilroy AV: Alison Kelly	Royal Free Host::Fausto Andreola AV: Lynn Knight
30 Apr 2024	David Abraham, Inflammation	Esther Geary / Jeannie Berkeley	'An integrated approach to risk stratification of early onset type 2 diabetes in low/middle income communities' Mohammed Al-Maadheed & Vidya Mohamed-Ali		Royal Free Host:Professor David Abraham AV: Millie Williams	Rayne Host::Professor David Lomas AV: Alison Kelly
07 May 2024	Dave Selwood, WIBR	Andrea Goncalves	'Therapeutic Compound Design of GEF-H1 in Models of Retinal Disease' Prof. Karl Matter, Inst. Ophthalmology & Prof. Edith Chan (WIBR)		Rayne Host: David Selwood AV: Alison Kelly	Royal Free Host::Professor Krista Rombouts AV: Lynn Knight
14 May 2024	Steve Halligan, Imaging	Alison Kelly	'Multimodal translational imaging of a humanised mouse model of cardiac transthyretin amyloidosis'. Dr Daniel Stuckey (Imaging) & Dr Ana Martinez-Naharro (National Amyloidosis Centre/Royal Free Hospital)		Rayne Host: Professor Mark Lythgoe AV: Catriona Heredia and Esther Geary	Royal Free Host: Guglielmo Verona AV: Millie Williams
21 May 2024	Rachel Chambers / Jeremy Brown, Respiratory	Nicole Halliday	'Precision Medicine in INterstitial Lung Disease' Dr. Helen Garthwaite (Consultant Respiratory Physician and Clinical Lead for Interstitial Lung disease Service, UCLH) & Prof. Joanna Porter (Professor of Resporatory Medicine, UCL)		Rayne Host: Rachel Chambers AV: Catriona Heredia	Royal Free Host: AV: Kate Henderson
04 Jun 2024	Krista Rombouts, ILDH	Lynn Knight	‘HepatiCan – a combined cell therapy and medical device for treatment of Acute Liver Failure (ALF)’. Dr Brian Hogan, Prof. Clare Selden		Royal Free Host: Fausto Andreola AV: Lynn Knight	Rayne Host: AV: Alison Kelly
11 Jun 2024	Cancelled seminar				Rayne Host: Derek Gilroy AV: Alison Kelly	Royal Free AV: Millie Williams
18 Jun 2024	Alan Salama Renal Medicine	Kate Henderson / Winnie Han Langner	'Can’t stand the heat? Unravelling the impact of the environment on kidney disease around the world'. Professor Ben Caplin		Royal Free Host: Alan Salama AV: Kate Henderson	Rayne AV: Alison Kelly
25 Jun 2024	David Abraham, Inflammation	Esther Geary / Jeannie Berkeley	“Demystifying rare forms of cardiac amyloidosis” Dr Aldostefano Porcari and Dr Diana Canetti	Amyloidosis Dr Diana Canetti	Royal Free Host: David Abraham AV: Millie Williams	Rayne AV: Alison Kelly
02 Jul 2024	Dave Selwood, WIBR	Andrea Goncalves	'Immune regulation, clinical outcomes and Th17-DC vaccination for ovarian cancer’ Professor Martin Cannon		Rayne Host: Professor Richard Stratton	Royal Free AV: Winnie
09 Jul 2024	Steve Halligan, Imaging	Alison Kelly	‘Non-invasive diagnosis/monitoring of brain disorders using novel MRI methods: application to gliomas and dementia’ Dr Jack Wells & Dr Harpreet Hyare		Rayne Host: Shereen Nizari AV: Alison Kelly	Royal Free AV: Lynn Knight
16 July 2024, 3pm start time	Derek Gilroy	Alison Kelly	'Nutrition misinformation: It’s pervasive, and probably more harmful than we think'. Sam Dicken and Stephan Guyenet		Rayne Host: Derek Gilroy AV: Alison Kelly	Royal Fee Host: AV: