BIOL2010
exam 2006
Answer four questions
1. Describe how the
segmented body plan of the Drosophila embryo is established.
2. Describe the
role of maternal gene products in mesoderm formation in Xenopus
3. Describe pre-implantation mouse development. Then write notes on TWO
of the following:
a) generating transgenic mice
by egg injection
b) knocking out genes in
embryonic stem (ES) cells
c) deriving embryonic stem
(ES) cells from mouse embryos
4. Write an essay on
signalling pathways involved in ageing
5. Compare eye development in vertebrates and Drosophila.
6. Describe what is known about the genes that determine sex in mammals.
How does the mammalian sex determination pathway compare with that
of invertebrates?
7. Discuss how vertebrate
limbs are specified and patterned
8. Write an essay on how
anterior-posterior and dorso-ventral patterning events contribute to the
different regions and cell types found in the mammalian central nervous system.
9. Describe
three different experimental methods that can be used to
investigate
processes during embryonic development (such as vascular
development,
axon guidance etc.) and discuss the advantages and limitations of
each approach.