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The latest job opportunities here at UCL Biochemical Engineering
PDRA in Scaling of Vaccine Bioprocessing Manufacturing
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Ref Number B04-04933
Professional Expertise Research and Research Support
Department UCL BEAMS (B04)
Location London
Working Pattern Full time
Salary £42,099–£50,585
Contract Type Fixed-term
Working Type On site
Available For Secondment No
Closing Date 07-June-2024
About us
This position is a key part of the Manufacturing Research Hub for a Sustainable Future (Vax-Hub Sustainable), led by UCL Biochemical Engineering and the University of Oxford with academic and industrial partners. Vax-Hub Sustainable is funded with a £12M EPSRC grant, part of UKRI. It builds on the success of the DHSC-funded Vax-Hub 1, which played a critical role in making the UK the global centre for vaccine discovery, development and manufacture. Its research underpinned the development of the ChAdOx-1 nCoV-19 vaccine, subsequently licensed to AstraZeneca, with benefit to over 180 countries. Vax-Hub Sustainable’s vision is to deliver manufacturing innovations that enable a transformative change towards sustainable and rapidly responsive vaccine manufacture.
About the role
The postholder will develop small scale and validated process sequences to facilitate the digitalisation of experimentation for vaccine bioprocess development. The project focuses on the development of an upstream-downstream process for one or more of the vaccine technologies available within the hub (mRNA, VLPs, viral vectored and glycoconjugates). There will be a high degree of interaction with UCL colleagues and industrial partners so excellent team-working and communication skills will be required. The post holder will be responsible for undertaking original experimental research, reporting on project progress and the preparation and submission of research papers arising from these and related studies.
About you
You hold a PhD in a relevant discipline (e.g. Bio/Chemical Engineering) or a related area or in natural sciences reinforced with an emphasis on scaling bioprocesses and/or interest in vaccines, and ideally possess experience in biochemical analyses, analytical procedures, molecular biology techniques, up and downstream process for vaccine production, scaling up/down approaches and miniaturization. We want to give people opportunity for development and this role is one where we could consider a wide range of different skills and experiences . Whilst all candidates must meet the essential criteria in order to be shortlisted, we actively encourage candidates who may not meet all of the desirable criteria to apply as we consider these to be areas the successful candidate can grow within the role. For informal enquiries, please contact Professor Martina Micheletti at m.micheletti@ucl.ac.uk
What we offer
As well as the exciting opportunities this role presents we also offer some great benefits some of which are below: • 41 Days holiday (including 27 days annual leave 8 bank holiday and 6 closure days) • Defined benefit career average revalued earnings pension scheme (CARE) • Cycle to work scheme and season ticket loan • On-Site nursery • On-site gym • Enhanced maternity, paternity and adoption pay • Employee assistance programme: Staff Support Service • Discounted medical insurance
Our commitment to Equality, Diversity and Inclusion
As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be under represented in UCL’s workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women. You can read more about our commitment to Equality, Diversity and Inclusion here: https://www.ucl.ac.uk/equality-diversity-inclusion/
Available documents
Research Fellow in Stem Cell Bioprocessing
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Ref NumberB04-04932
Professional ExpertiseResearch and Research Support
Department UCL BEAMS (B04)
Location London
Working Pattern Full time
Salary £42,099–£50,585
Contract Type Fixed-term
Working Type On site
Available For Secondment No
Closing Date 09-May-2024
About us
UCL Biochemical Engineering is seeking to appoint a Postdoctoral Fellow on a fixed-term of 36 months with possibility of extension to be part of the growing UCL Cellular Agriculture Research Group led by Dr Petra Hanga (https://profiles.ucl.ac.uk/84339-petra-hanga) and the newly EPSRC/UKRI-funded Cellular Agriculture Manufacturing Hub (CARMA). CARMA is a £12M hub that aims to transform food production, transitioning to an environmentally, economically, and socially sustainable model in which novel manufacturing systems complement traditional food production. Cellular Agriculture will enable the manufacture of staple foods, such as meat, without the environmental and land impacts of traditional farming and associated ethical issues.
About the role
This exciting project will focus on designing manufacturing technologies for high cell yield at scale. It will explore methods for process intensification to enhance cell yields and reduce resource use and associated costs. These will also include explorations of media recycling and waste valorisation. Scale-up of these developed strategies/technologies will be an integral aspect of this project. This is a fixed-term role of 36 months with possibility of extension. For full description of the duties and responsibilities, please consult the Job Description document.
About you
The successful applicant will have a PhD in a relevant subject (e.g. biochemical engineering, bioprocessing, regenerative medicine, tissue engineering etc), significant experience with mammalian cell culture and knowledge and experience of working with stirred tank bioreactors. Experience of working with stem cells and hydrogels/biomaterials is highly desirable. Excellent organisational, planning and time management skills are essential. The ability to work both independently and as part of a team, and a flexible approach to problem-solving are required. You should have excellent communication skills and a demonstrated ability to carry out high quality original research, leading to publication in peer-reviewed journals. The ability to project manage parallel research work packages and to work to deadlines is also essential. If you have any queries about the role, please contact m.hanga@ucl.ac.uk.
What we offer
For information about our rewards and benefits please visit: https://www.ucl.ac.uk/work-at-ucl/reward-and-benefits.
Our commitment to Equality, Diversity and Inclusion
As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL’s workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women. You can read more about our commitment to Equality, Diversity and Inclusion here: https://www.ucl.ac.uk/equality-diversity-inclusion/.
Available documents
Laboratory Technician (Upstream Bioprocess Training)
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Ref Number B04-04990
Professional Expertise Laboratory Technical and Lab Support
Department UCL BEAMS (B04)
Location UCL East
Working Pattern Full time
Salary £42,099–£50,585
Contract Type Fixed-term
Working Type On site
Available For Secondment No
Closing Date 26-May-2024
About us
University College London (UCL) is a university with a population of over 43,800 undergraduate and postgraduate students from more than 150 different countries. UCL is committed to being a world leader in the integration of education and research, underpinning an inspirational student experience. For more information see: www.ucl.ac.uk. In our single biggest development since we were founded, UCL is expanding to East London. Located on the Queen Elizabeth Olympic Park, UCL East will be dedicated to disruptive thinking and discovery across disciplines and beyond academic walls, to find solutions to the biggest challenges for future living. We are located in Newham, East London - one of the most socially diverse parts of the UK – and we would like our staff recruitment to reflect this. Opening in 2022 and 2023, UCL East will unite academic activities across experiments, arts, society and technology, integrating research and education, theory and practice – with cross-disciplinarity, innovation and public engagement. More than just a conventional university campus, UCL East represents a future focused mindset. We will deliver new research, technology and innovation, and undergraduate and postgraduate degree programmes for up to 4,000 students. This post sits within the Manufacturing Futures Lab (MFL) in the Marshgate Building at UCL East, with 1500m2 of collaborative research laboratories. The MFL is a cross-faculty hub, bringing together researchers from UCL departments of Biochemical Engineering, Chemical Engineering, Mechanical Engineering and from Chemistry, with the Department of Biochemical Engineering as the lead partner for this post. UCL is committed to an inclusive and supportive culture for all. In recruiting, we welcome the unique contributions that everyone can bring in terms of their education, opinions, culture, ethnicity, race, sex, gender identity and expression, nation of origin, age, languages spoken, religion, disability, sexual orientation and beliefs. We continually strive to have the systems in place to ensure that all members of the university have equal access to opportunities, reach their full potential and maintain a work-life balance.
About the role
The main purpose of the job is to develop practical laboratory-based training modules related to upstream bioprocess operations i.e. fermentation and cell culture. The role is part of the RESILIENCE UK Centre of Excellence (CoE) in Medicines Manufacturing which is a collaborative activity between the University of Birmingham, UCL, Heriot Watt and Teesside Universities. The post-holder will be expected to work with a RESILIENCE CoE technician responsible for downstream process development training programmes as well as interact with other technical staff involved in supporting MFL teaching programmes and facilities. The technical support will involve designing and implementing training courses for a wide range of individuals working in the industrial, academic, healthcare (NHS) sectors as well as secondary, higher, and further education institutions. . It will also involve the use of Virtual Reality (VR) technologies to support and enhance training delivery. This work will develop RESILIENCE into a self-sustaining initiative that will provide significant, long-term benefit and achieve its strategic objectives focussed on sustainable contribution to the national work force for medicines manufacturing. Delivery of the UCL RESILIENCE objectives is enabled by new facilities available to us at UCL East and within the UCL East Manufacturing Futures Lab [https://www.ucl.ac.uk/manufacturing-futures-lab/ucl-manufacturing-future.... These include new outreach and engagement spaces, teaching wetlabs and a Management Education Suite where we will deliver some of our new MBI Training Programme modules [https://www.ucl.ac.uk/biochemical-engineering/study/industrial-training/.... This post is funded for 2 years in the first instance.
About you
The postholder should have experience in a teaching and/or research laboratory and particular expertise in the aseptic culture of microbial and/or mammalian cells in laboratory and pilot scale bioreactors. They should also have significant technical experience in the design, operation and maintenance of related laboratory equipment and instruments; significant experience of laboratory (biological) safety management; and experience of management and training of others in the use of equipment they are responsible for.
What we offer
As well as the exciting opportunities this role presents we also offer other benefits such as: 41 Days holiday (including 27 days annual leave, 8 bank holiday and 6 closure days); Hybrid Final Salary Pension Scheme; Cycle to work scheme and season ticket loan; Enhanced maternity, paternity and adoption pay; Employee assistance programme; Staff Support Service; Discounted medical insurance
Our commitment to Equality, Diversity and Inclusion
As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL’s workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women. You can read more about our commitment to Equality, Diversity and Inclusion here: https://www.ucl.ac.uk/equality-diversity-inclusion/
Available documents
Laboratory Technician (Downstream Bioprocess Training)
Apply here
Ref Number B04-04989
Professional Expertise Laboratory Technical and Lab Support
Department UCL BEAMS (B04)
Location UCL East
Working Pattern Full time
Salary £42,099–£50,585
Contract Type Fixed-term
Working Type On site
Available For Secondment No
Closing Date 26-May-2024
About us
University College London (UCL) is a university with a population of over 43,800 undergraduate and postgraduate students from more than 150 different countries. UCL is committed to being a world leader in the integration of education and research, underpinning an inspirational student experience. For more information see: www.ucl.ac.uk. In our single biggest development since we were founded, UCL is expanding to East London. Located on the Queen Elizabeth Olympic Park, UCL East will be dedicated to disruptive thinking and discovery across disciplines and beyond academic walls, to find solutions to the biggest challenges for future living. We are located in Newham, East London - one of the most socially diverse parts of the UK – and we would like our staff recruitment to reflect this. Opening in 2022 and 2023, UCL East will unite academic activities across experiments, arts, society and technology, integrating research and education, theory and practice – with cross-disciplinarity, innovation and public engagement. More than just a conventional university campus, UCL East represents a future focused mindset. We will deliver new research, technology and innovation, and undergraduate and postgraduate degree programmes for up to 4,000 students. This post sits within the Manufacturing Futures Lab (MFL) in the Marshgate Building at UCL East, with 1500m2 of collaborative research laboratories. The MFL is a cross-faculty hub, bringing together researchers from UCL departments of Biochemical Engineering, Chemical Engineering, Mechanical Engineering and from Chemistry, with the Department of Biochemical Engineering as the lead partner for this post. UCL is committed to an inclusive and supportive culture for all. In recruiting, we welcome the unique contributions that everyone can bring in terms of their education, opinions, culture, ethnicity, race, sex, gender identity and expression, nation of origin, age, languages spoken, religion, disability, sexual orientation and beliefs. We continually strive to have the systems in place to ensure that all members of the university have equal access to opportunities, reach their full potential and maintain a work-life balance.
About the role
The main purpose of the job is to develop practical laboratory-based training modules related to downstream bioprocess operations and related analytical techniques. The role is part of the RESILIENCE UK Centre of Excellence (CoE) in Medicines Manufacturing which is a collaborative activity between the University of Birmingham, UCL, Heriot Watt and Teesside Universities. The post-holder will be expected to work with a RESILIENCE CoE technician responsible for upstream process development training programmes as well as interact with other technical staff involved in supporting MFL teaching programmes and facilities. The technical support will involve designing and implementing training courses for a wide range of individuals working in the industrial, academic, healthcare (NHS) sectors as well as secondary, higher, and further education institutions. . It will also involve the use of Virtual Reality (VR) technologies to support and enhance training delivery. This work will develop RESILIENCE into a self-sustaining initiative that will provide significant, long-term benefit and achieve its strategic objectives focussed on sustainable contribution to the national work force for medicines manufacturing. Delivery of the UCL RESILIENCE objectives is enabled by the new facilities available to us at UCL East and within the UCL East Manufacturing Futures Lab [https://www.ucl.ac.uk/manufacturing-futures-lab/ucl-manufacturing-future.... These include new outreach and engagement spaces, teaching wetlabs and the Management Education Suite where we will deliver some of our new MBI Training Programme modules [https://www.ucl.ac.uk/biochemical-engineering/study/industrial-training/.... This post is funded for 2 years in the first instance.
About you
The postholder should have experience working in a teaching and/or research laboratory and particular expertise in key downstream processing approaches, i.e., filtration, centrifugation, chromatography etc. They should also have expertise in relevant analytical techniques such as molecular biology (PCR, RT-PCR), protein biochemistry (immunocytochemistry, immunoblotting, ELISA), and colorimetric cell staining techniques. They should also have significant technical experience in the design, operation and maintenance of related laboratory equipment and instruments; significant experience of laboratory (biological) safety management; and experience of management and training of others in the use of equipment they are responsible for.
What we offer
As well as the exciting opportunities this role presents we also offer other benefits such as: 41 Days holiday (including 27 days annual leave, 8 bank holiday and 6 closure days); Hybrid Final Salary Pension Scheme; Cycle to work scheme and season ticket loan; Enhanced maternity, paternity and adoption pay; Employee assistance programme; Staff Support Service; Discounted medical insurance
Our commitment to Equality, Diversity and Inclusion
As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL’s workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women. You can read more about our commitment to Equality, Diversity and Inclusion here: https://www.ucl.ac.uk/equality-diversity-inclusion/