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My project aims to understand the molecular events during
neural specification. In order to build a
functional network and identify genetic interactions and hierarchies I
will take advantage of a combination of next-generation technologies (RNA-seq,
ChIP-seq and NanoString nCounter)
Telephone (Office): 020 3108 4045 Email: n.moncaut@ucl.ac.uk |
Profile
1996-2002.
Degree in Biological Sciences. Orientation: Animal Physiology. School of
Exacts and Natural Sciences, University of Buenos Aires, Argentina.
2002-2007. PhD Thesis at the Instituto de Ciências Biomédicas
Abel Salazar, University of Porto, Portugal. "Evolution of GnRH receptors in
European sea bass, Dicentrarchus labrax: structure and function."
Supervisors: Adelino V.M. Canário (Center of Marine Sciences, University of
Algarve, Portugal) and Gustavo M. Somoza (Institute of Biotechnological
Research, Argentina).
2007-2008. Postdoctoral researcher with Prof Moisés Mallo,
Instituto Gulbenkian de Ciência, Portugal.
2008-2012. Postdoctoral researcher with Prof Peter W.J.
Rigby, The Institute of Cancer Research, London, UK.
2012-present Postdoctoral researcher with Prof Claudio Stern,
University College London, UK
Publications
- Moncaut N, Cross JW, Siligan C, Keith A, Taylor K, Rigby PWJ and Carvajal JJ. Musculin and Tcf21 coordinate the maintenance of myogenic regulatory factor expression levels during mouse craniofacial development. Development 2012 139: 958-967.
- Ribas R, Moncaut N, Siligan C, Taylor K, Cross JW, Rigby PW, Carvajal JJ. Members of the TEAD family of transcription factors regulate the expression of Myf5 in ventral somitic compartments. Developmental Biology 2011 355(2):372-80.
- Vinagre T, Moncaut N, Carapuço M, Nóvoa A, Bom J, Mallo M. Evidence for a myotomal Hox/Myf cascade governing nonautonomous control of rib specification within global vertebral domains. Developmental Cell 2010 18(4):655-61.
- Schiedlmeier B, Santos AC, Ribeiro A, Moncaut N, Lesinski D, Auer H, Kornacker K, Ostertag W, Baum C, Mallo M, Klump H. "HOXB4's road map to stem cell expansion". Proceedings of the National Academy of Science U S A 2007 104(43):16952-7.
- Guilgur L*, Moncaut N*, Canário A, Somoza G. A review on the evolution of GnRH ligands and receptors in gnathostomates. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 2006, 144(3): 272-283. (*equal contribution)
- Moncaut N, Somoza G, Power D and Canário A. Five gonadotrophin-releasing hormone receptors in a teleost fish: Isolation, tissue distribution and phylogenetic relationships. Journal of Molecular Endocrinology (2005) 34, 767-779.
- Strobl-Mazzulla P, Moncaut N, López G, Miranda L, Canario A and Somoza G. "Brain aromatase from pejerrey fish (Odontesthes bonariensis): cDNA cloning, tissue expression, and immunohistochemical localization." General and Comparative Endocrinology 143 (2005) 21-32.
- Moncaut N, Lo Nostro F and Maggese MC. Vitellogenin detection in surface mucus of the South American cichlid fish Cichlasoma dimerus (Heckel, 1840) induced by estradiol-17beta. Effects on liver and gonads. Aquatic Toxicology 63 (2003) 127-137.