CRUK City of London Centre 2020 symposium

Programme

08:30-09:00 - Registration

09:00-09:10 - Welcome - Professor Tariq Enver

09:10-10:40 - Session 1 - Cancer evolution and tumour heterogeneity

Chair: Professor Francesca Ciccarelli

• 09:10-09:30 - Targeting Wnt signalling in colorectal cancer - Dr Vivian Li
• 09:30-09:50 - Post-translationally spliced epitopes of cancer cells - Dr Michele Mishto
• 09:50-10:10 - Probing the evolution heterogeneity in follicular lymphoma - Dr Giuseppe Palladino
• 10:10-10:40 - CoL Centre Student talks

10:40-11:00 - Tea break

11:00-12:20 - Session 2 - Cross-disciplinary approaches enhancing biotherapeutics

• Chair: Professor Kairbaan Hodivala-Dilke
• 11:00-11:20 - Molecular imaging in cancer – new radiotracers for treatment decision-making - Professor Philip Blower
• 11:20-11:40 - Mechanisms of tumour heterogeneity - Dr Axel Behrens
• 11:40-11:50 - CoL Centre Development fund:
  Connecting Single-Cell Ligands, Receptors, and Signals in Tumour Microenvironment Organoids - Dr Chris Tape
• 11:50-12:00 - CoL Centre Student talks
• 12:00-12:20 - Combining Imaging and Mathematical Modelling to Reconstruct Virtual Tumours - Professor Rebecca Shipley
• 12:20-12:40 - Radnet
  Cancer Research UK RadNet City of London Radiation Research Unit - Professor Gary Royle and Dr Erik Sahai

12:40-13:40 - Lunch

13:40-15:00 - Session 3 - Developing Biological Therapies

Chair: Dr Erik Sahai

• 13:40-14:00 - Title TBC - Professor Sergio Quezada
• 14:00-14:20 - Heme oxygenase-1 expressing macrophages in cancer: the wrong place at the wrong time - Dr James Arnold
• 14:20-14:40 - Targeting L-arginine as a novel cancer therapy - Professor Peter Szlosarek
• 14:40-14:50 - CoL Centre Development fund
• Deep Learning of High Dimensional Genetic, Immune and Clinical Parameters to Predict Patient Response to Immune Checkpoint Blockade - Professor Francesca Ciccarelli
• 14:50-15:00 - CoL Centre Student talks

15:00-15:30 - Tea break

15:30-16:40 - Session 4 - Paediatrics Cross-cutting Theme

Chairs: Professors Pamela Kearns and Josef Vormoor

• 15:30-15:50 - Epigenetic deregulation in malignant brain tumours - Professor Silvia Marino
• 15:50-16:10 - Senescence in Cancer: Protumourigenic Activities and Novel Therapies - Professor JP Martinez-Barbera
• 16:10-16:30 - Title TBC - Dr Sara Ghorashian
• 16:30-16:40 - CoL Centre Student talks

16:40-17:00 Closing remarks - Professor Anton Berns

17:00-19:00 Drinks Reception

The Symposium will highlight stimulating talks cross-cutting the City of London Centre themes including:

• Theme 1: Developing Biological Therapies
• Theme 2: Cross-disciplinary Approaches Enhancing Biotherapeutics
• Theme 3: Cancer Evolution and Tumour Heterogeneity
• RadNet
• Paediatrics Cross-cutting Theme
• Training Cross-cutting Theme