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Multiple Myeloma Lab - Prof Kwee Yong
- Lee L, Bounds D, Paterson J, Herledan G, Sully K, Seestaller-Wehr L M, Fieles W E, Tunstead J, Germaschewski F, Mayes P, Craigen J, Yong KL. (2016) Evaluation of B Cell Maturation Antigen as a Target for Antibody Drug Conjugate Mediated Cytotoxicity in Multiple Myeloma. British Journal of Haematology, 17 June 2016. doi:10.1111/bjh.14145.
- Kassen D, Lath D, Lach A, Evans H, Chantry A, Rabin N, Croucher P, and Yong KL. (2016) Myeloma Impairs Mature Osteoblast Function but Causes Early Expansion of Osteo-Progenitors: Temporal Changes in Bone Physiology and Gene Expression in the KMS12BM Model. British Journal of Haematology 172:64-79
- Smith, Dean, David Mann, and Kwee Yong. (2016) Cyclin D Type Does Not Influence Cell Cycle Response to DNA Damage Caused by Ionizing Radiation in Multiple Myeloma Tumours. British Journal of Haematology 173, no. 5 (June 2016): 693–704. doi:10.1111/bjh.13982.
- Sive, Jonathan I., Andrew Feber, Dean Smith, John Quinn, Stephan Beck, and Kwee Yong. (2016) ‘Global Hypomethylation in Myeloma Is Associated with Poor Prognosis’. British Journal of Haematology 172, no. 3 (February 2016): 473–75. doi:10.1111/bjh.13506.
- Sive, Jonathan I., Andrew Feber, Dean Smith, John Quinn, Stephan Beck, and Kwee Yong. (2016) ‘Global Hypomethylation in Myeloma Is Associated with Poor Prognosis’. British Journal of Haematology 172, no. 3 (February 2016): 473–75. doi:10.1111/bjh.13506.
- Smith D, Armenteros E, Percy L, Kumar M, Lach A, Herledan G, Stubbs M, Downward J, and Yong KL. (2015) RAS Mutation Status and Bortezomib Therapy for Relapsed Multiple Myeloma. British Journal of Haematology 169, no. 6 (June 2015): 905–8. doi:10.1111/bjh.13258.
- Kassen D, Moore S, Percy L, Herledan G, Bounds D, Rodriguez-Justo M, Yong KL. (2014) The bone marrow stromal compartment in multiple myeloma patients retains capability for osteogenic differentiation in vitro: defining the stromal defect in myeloma. British Journal of Haematology 167: 194-206
- **Rabin N, Percy L, Khan I, Quinn J, D’Sa S, Yong KL (2012) Improved response with post-ASCT consolidation by low dose thalidomide, cyclophosphamide and dexamethasone as first line treatment for multiple myeloma. Br J Haematol 2012 June 19 (epub) Pubmed
- **Percy LA, Moore SE, Qian W, Dorman J, Rabin N, Watts M, Linch DC, Yong KL. (2012) Re-infused lymphocyte dose does not influence disease control following upfront autologous stem cell transplantation for multiple myeloma. Br J Haematol; 157:1365
- Stengel C, Cheung CW, Quinn J, Yong K, and Khwaja A. (2012) Optimal Induction of Myeloma Cell Death Requires Dual Blockade of Phosphoinositide 3-kinase and mTOR Signalling and Is Determined by Translocation Subtype. Leukemia 26:1761-1770.
- Glassford J, Kassen D, Quinn J, Stengel C, Kallinikou K, Khwaja A, Yong KL (2011). Inhibition of cell cycle progression by dual phosphatidylinositol-3-kinase and mTOR blockade in cyclin D2 positive multiple myeloma bearing IgH translocations. Blood Cancer Journal e50 doi:10.1038/bcj.2011.44
- Quinn, J., Glassford, J., Percy, L., Munson, P., Marafioti, T., Rodriguez-justo, M., Yong, K. (2011). APRIL promotes cell cycle progression in primary multiple myeloma cells: influence of D-type cyclin group and translocation status. Blood 117:890-901
- Quinn, J., Percy, L., Glassford, J., Somana, K., Rodriguez-justo, M., Yong, K. (2010). CD20-positive multiple myeloma - differential expression of cyclins D1 and D2 suggests a heterogeneous disease. British Journal of Haematology 149(1), 156-159
- Kyriakou, C., Rabin, N., Pizzey, A., Nathwani, A., Yong, K. (2008). Short term homing of human bone marrow derived mesenchymal stem cells (hMSCs) in a xenogeneic animal model is influenced by animal age and is increased by enforced expression of CXCR4. Haematologica 93(10), 1457-1465
- Glassford, J., Rabin, N., Lam, E. W., Yong, K. L. (2007). Functional regulation of D-type cyclins by insulin-like growth factor-I and serum in multiple myeloma cells. British Journal of Haematology 139(2), 243-254
- Rabin, N., Kyriakou, C., Coulton, L., Gallagher, O. M., Buckle, C., Benjamin, R., Singh, N., Glassford, J., Otsuki, T., Nathwani, A. C., Croucher, P. I., Yong, K. L. (2007). A new xenograft model of myeloma bone disease demonstrating the efficacy of human mesenchymal stem cells expressing osteoprotegerin by lentiviral gene transfer. Leukemia 21:2181-2191
