Preprints

COVID-19 Longitudinal Health and Wellbeing National Core Study

Mental Health

Mental Health

Coming Soon

Healthcare Disruption: Healthcare Disruption
Accident and emergency (AE) attendance in England following infection with SARS-CoV-2 Omicron or Delta
Daniel J. Grint , Kevin Wing , Hamish P. Gibbs , Stephen JW Evans , Elizabeth Williamson , Krishnan Bhaskaran , Helen I McDonald , Alex J. Walker , David Evans , George Hickman , Rohini Mathur , Anna Schultze , Christopher T Rentsch , John Tazare , Ian J Douglas , Helen J. Curtis , Caroline E Morton , Sebastian Bacon , Simon Davy , Brian MacKenna , Peter Inglesby , Richard Croker , John Parry , Frank Hester , Sam Harper , Nicholas J DeVito , Will Hulme , Chris Bates , Jonathon Cockburn , Amir Mehrkar , Ben Goldacre , Rosalind M. Eggo , Laurie Tomlinson Full Text

Society and Health: Society and Health
Coming Soon

Vaccination

Vaccination

Effectiveness of BNT162b2 booster doses in England: an observational study in OpenSAFELY-TPP

William J Hulme, Elizabeth J Williamson, Elsie Horne, Amelia Green, Linda Nab, Ruth Keogh, Edward PK Parker, Venexia Walker, Tom Palmer, Helen Curtis, Milan Wiedemann, Christine Cunningham, Alex J Walker, Louis Fisher, Brian MacKenna, Christopher T Rentsch, Anna Schultze, Krishnan Bhaskaran, John Tazare, Laurie Tomlinson, Helen I McDonald, Caroline E Morton, Richard Croker, Colm Andrews, Robin Parks, Lisa Hopcroft, Jon Massey, Jessica Morley, Amir Mehrkar, Seb Bacon, Dave Evans, Peter Inglesby, George Hickman, Simon Davy, Iain Dillingham, Tom Ward, Viyasaan Mahalingasivam, Bang Zheng, Ian J Douglas, Stephen JW Evans, Chris Bates, Jonathan AC Sterne, Miguel A Hernán, Ben Goldacre Full Text

Other

Other

Metformin and outcomes in COVID-19 infection: an electronic cohort study from Wales, UK

James Coulson, Mike Seaborne, Robert Bracchi, Murugarajan Athiyappan, Sinead Brophy Full Text

Comparative effectivness of sotrovimab and molnupiravir for preventing COVID-19 outcomes in non-hospitalised patients on kidney replacement therapy: observational cohort study using the OpenSAFELY-UKRR linked platform and SRR database

The OpenSAFELY Collaborative, Bang Zheng, Jacqueline Campbell, EdwardJ Carr, John Tazare, Linda Nab, Viyaasan Mahalingasivam, Amir Mehrkar, Shalini Santhakumaran, Retha Steenkamp, Fiona Loud, Susan Lyon, Miranda Scanlon, William J Hulme, Amelia CA Green, Helen J Curtis, Louis Fisher, Edward Parker, Ben Goldacre, Ian Douglas, Stephen Evans, Brian MacKenna, Samira Bell, Laurie A Tomlinson, Dorothea Nitsch, The LH&W NCS (or CONVALESCENCE) Collaborative Full Text

Changes in the rate of cardiometabolic and pulmonary events during the COVID-19 pandemic

Alex J Walker, John Tazare, George Hickman, Christopher T Rentsch, Elizabeth J Williamson, Krishnan Bhaskaran, David Evans, Kevin Wing, Rohini Mathur, Angel YS Wong, Anna Schultze, Sebastian CJ Bacon, Chris Bates, Caroline E Morton, Helen J Curtis, Emily Nightingale, Helen I McDonald, Amir Mehrkar, Peter Inglesby, Brian MacKenna, Jonathan Cockburn, William J Hulme, Harriet Forbes, Caroline Minassian, Richard Croker, John Parry, Frank Hester, Sam Harper, Rosalind M Eggo, Stephen JW Evans, Liam Smeeth, Ian J Douglas, Laurie Tomlinson, Ben Goldacre Full Text

Impact of voluntary risk-mitigation behaviour on transmission of the Omicron SARS-CoV-2 variant in England

Ellen Brooks-Pollock, Kate Northstone, Lorenzo Pellis, Francesca Scarabel, Amy Thomas, Emily Nixon, David A. Matthews, Claire J. Steves, Vicky Bower, Maria Paz Garcia, Nicholas J. Timpson, Leon Danon Full Text

Convalescence Study

Long COVID Definition

Fit notes associated with COVID-19 in 24 million patients’ primary care records: A cohort study in OpenSAFELY-TPP

Andrea L Schaffer, Robin Y Park, John Tazare, Krishnan Bhaskaran, Brian MacKenna, Spiros Denaxas, Iain Dillingham, Sebastian CJ Bacon, Amir Mehrkar, Chris Bates, Ben Goldacre, Felix Greaves, John Macleod, The OpenSAFELY Collaborative, National Core Studies Collaborative, Laurie A Tomlinson, Alex J Walker full text

Long COVID Outcomes

Long COVID Outcomes

Cardiovascular events following SARS-CoV-2 infection (preprint) - Diabetes events following SARS-CoV-2 infection (preprint) - Mental Health events following SARS-CoV-2 infection

Genevieve Cezard, Rachel Denholm, Yinghui Wei,Lucy Teece, Renin Toms, Harriet Forbes, Alex Walker, Louis Fisher, Elsie Horne, Kurt Taylor, Tom Palmer, Marwa Al Arab, Jose Cuitun, Samantha Ip, Simon Davy, Iain Dillingham, Sebastian Bacon, Amir Mehrkar, Caroline Morton, Felix Greaves, Catherine Hyams, George Davey Smith, John MacLeod, Nishi Chaturvedi, Ben Goldacre, William Whiteley, Angela Wood, Jonathan Sterne, Venexia Walker full text

Diabetes following SARS-CoV-2 infection: Incidence, persistence, and implications of COVID-19 vaccination. A cohort study of fifteen million people

Kurt Taylor, Sophie Eastwood, Venexia Walker, Genevieve Cezard, Rochelle Knight, Marwa Al Arab, Yinghui Wei, Elsie M F Horne, Lucy Teece, Harriet Forbes, Alex Walker, Louis Fisher, Jon Massey, Lisa E M Hopcroft, Tom Palmer, Jose Cuitun Coronado, Samantha Ip, Simon Davy, Iain Dillingham, Caroline Morton, Felix Greaves, John Macleod, Ben Goldacre, Angela Wood, Nishi Chaturvedi, Jonathan A C Sterne, Rachel Denholm, CONVALESCENCE study, The OpenSAFELY collaborative The Longitudinal Health and Wellbeing and Data and Connectivity UK COVID-19 National Core Studies full text

Impact of COVID-19 on mental illness in vaccinated and unvaccinated people: a population-based cohort study in OpenSAFELY

Venexia M Walker, Praveetha Patalay, Jose Ignacio Cuitun Coronado, Rachel Denholm, Harriet Forbes, Jean Stafford, Bettina Moltrecht, Tom Palmer, Alex Walker, Ellen J. Thompson, Kurt Taylor, Genevieve Cezard, Elsie M F Horne, Yinghui Wei, Marwa Al Arab, Rochelle Knight, Louis Fisher, Jon Massey, Simon Davy, Amir Mehrkar, Seb Bacon, Ben Goldacre, Angela Wood, Nishi Chaturvedi, John Macleod, Ann John, Jonathan A C Sterne the Longitudinal Health and Wellbeing COVID-19 National Core Study full text

Long COVID Risk Factors

Patient characteristics associated with clinically coded long COVID: an OpenSAFELY study using electronic health records

Yinghui Wei, Elsie MF Horne, Rochelle Knight, Genevieve Cezard, Alex Walker, Louis Fisher, Rachel Denholm, Kurt Taylor, Venexia Walker, Stephanie Riley, Dylan M Williams, Robert Willans, Simon Davy, Sebastian Bacon, Ben Goldacre, Amir Mehrkar, Spiros Denaxas, Felix Greaves, Richard J Silverwood, Aziz Sheikh, Nish Chaturvedi, Angela M Wood, John Macleod, Claire Steves, Jonathan AC Sterne the UK COVID-19 Longitudinal Health and Wellbeing National Core Study and CONVALESCENCE study full text

Long COVID longitudinal Qualitative Study: Coming soon

Deep Phenotyping Clinic: Coming Soon