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Institute of Immunity and Transplantation

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What we do

At the Institute of Immunity and Transplantation, we develop vaccines and therapies to boost the immune system in patients with cancer and chronic infections. We also aim to induce tolerance in patients with autoimmune disease and after kidney and liver transplantation.

An amazing life, that I can just stay in one place

Angelika Holler has worked in Professor Hans Stauss' laboratory for 23 years. She reflects on the contrast between the solitariness of scientific projects and the richness of the community that forms around it, as well as her life outside of the lab.

Angelika Holler's Profile

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The IIT is a world-class centre of excellence dedicated to the study of the immune system. While the immune system plays an important role in protecting people against infection by viruses and bacteria, it is also critical in maintaining lifelong health.

Solving complex problems

The IIT brings together scientists, clinicians and patients in one space so that we can collaborate and bring our expertise to solve complex illnesses, such as diabetes and hepatitis.

Working with patients

We treat patients at the nearby Royal Free Hospital. The Pears Building, where we are based, includes accommodation for Royal Free Hospital patients and relatives.

Pooling our expertise

By collaborating with each other and exchanging ideas and expertise in a single space, we can speed up the clinical trials and delivery of new immunotherapies and treatments.

Tackling diseases

Our experts are working on new therapies and treatments for a range of conditions. Find out more about how we're tackling some of these disorders and what we've achieved so far.

Layout featuring colorized 3D print imagery of hepatitis B virus. Note: Not to scale. Credit: NIAID

Combating hepatitis B

Hepatitis B is one of the top ten killer diseases in the world. Professor Mala Maini tells us how she and her team are tackling this deadly infection.

Cell structure

Treating inherited immune defects

The key to success in treating patients with immune deficiency is working with scientists with insights into particular parts of the immune system.

Beta cells on the pancreas surface, insulin and leukocytes inside the blood vessel

Tackling type 1 diabetes

Around 400,000 people in the UK have type 1 diabetes. Professor Lucy Walker explains her working to prevent this increasingly prevalent disease.

A look within: from the middle of nowhere to the biggest city in the UK

Dr Sam Burgess is a Research Fellow specialising in the efficacy of T-cells to improve therapies and treatments. Sam talks about taking on advice and absorbing skills over the course of his early career. He also reflects on the fast pace and constant activity of London, which keeps him occupied as a self-confessed 'fidget'.

Sam Burgess' Profile

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