XClose

Division of Infection and Immunity

Home
Menu

2021 publications

2021 publications 

Maitra A, Solanki P, Sadouki Z, McHugh TD, Kloprogge F. Improving the Drug Development Pipeline for Mycobacteria: Modelling Antibiotic Exposure in the Hollow Fibre Infection Model. Antibiotics (Basel). 2021 Dec 10;10(12):1515. doi: 10.3390/antibiotics10121515

Tiberi S, Vjecha MJ, Zumla A, Galvin J, Migliori GB, Zumla A. Accelerating development of new shorter TB treatment regimens in anticipation of a resurgence of multi-drug resistant TB due to the COVID-19 pandemic. Int J Infect Dis. 2021 Dec;113 Suppl 1:S96-S99. doi: 10.1016/j.ijid.2021.02.067. Epub 2021 Mar 10. 

Shield CG, Swift BMC, McHugh TD, Dedrick RM, Hatfull GF, Satta G. Application of Bacteriophages for Mycobacterial Infections, from Diagnosis to Treatment. Microorganisms. 2021 Nov 16;9(11):2366. doi: 10.3390/microorganisms9112366

Fonseca JD, Mavrides DE, Graham PA, McHugh TD. Results of urinary bacterial cultures and antibiotic susceptibility testing of dogs and cats in the UK. J Small Anim Pract. 2021 Dec;62(12):1085-1091. doi: 10.1111/jsap.13406. Epub 2021 Aug 31.

High J, Enne VI, Barber JA, Brealey D, Turner DA, Horne R, Peters M, Dhesi Z, Wagner AP, Pandolfo AM, Stirling S, Russell C, O'Grady J, Swart AM, Gant V, Livermore DM; INHALE Study Group. INHALE: the impact of using FilmArray Pneumonia Panel molecular diagnostics for hospital-acquired and ventilator-associated pneumonia on antimicrobial stewardship and patient outcomes in UK Critical Care-study protocol for a multicentre randomised controlled trial. Trials. 2021 Oct 7;22(1):680. doi: 10.1186/s13063-021-05618-6

Wey EQ, Bristow C, Nandani A, O'Farrell B, Pang J, Lanzman M, Yang S, Ho S, Mack D, Spiro M, Balakrishnan I, Bhagani S, Pollara G. Preserved C-reactive protein responses to blood stream infections following tocilizumab treatment for COVID-19. J Infect. 2021 Nov;83(5):607-635. doi: 10.1016/j.jinf.2021.08.017. Epub 2021 Aug 14.

Lipman M, McQuaid CF, Abubakar I, Khan M, Kranzer K, McHugh TD, Padmapriyadarsini C, Rangaka MX, Stoker N. The impact of COVID-19 on global tuberculosis control. Indian J Med Res. 2021 Apr;153(4):404-408. doi: 10.4103/ijmr.IJMR_326_21

Mavrides DE, Morgan AL, Na JG, Graham PA, McHugh TD. Antimicrobial resistance profiles of bacteria associated with lower respiratory tract infections in cats and dogs in England. Vet Rec. 2022 Feb;190(4):e779. doi: 10.1002/vetr.779. Epub 2021 Aug 11.

Partridge SR, Enne VI, Grohmann E, Hall RM, Rood JI, Roy PH, Thomas CM, Firth N. Classifying mobile genetic elements and their interactions from sequence data: The importance of existing biological knowledge. Proc Natl Acad Sci U S A. 2021 Aug 31;118(35):e2104685118. doi: 10.1073/pnas.2104685118

Fernández J, Piano S, Bartoletti M, Wey EQ. Management of bacterial and fungal infections in cirrhosis: The MDRO challenge. J Hepatol. 2021 Jul;75 Suppl 1:S101-S117. doi: 10.1016/j.jhep.2020.11.010

Paleckyte A, Dissanayake O, Mpagama S, Lipman MC, McHugh TD. Reducing the risk of tuberculosis transmission for HCWs in high incidence settings. Antimicrob Resist Infect Control. 2021 Jul 19;10(1):106. doi: 10.1186/s13756-021-00975-y

Kloprogge F, Abubakar I, Esmail H, Hack V, Kunst H, McHugh TD, Noursadeghi M, Surey J, Tiberi S, Lipman M. Exploring a combined biomarker for tuberculosis treatment response: protocol for a prospective observational cohort study. BMJ Open. 2021 Jul 8;11(7):e052885. doi: 10.1136/bmjopen-2021-052885

Pandolfo AM, Horne R, Jani Y, Reader TW, Bidad N, Brealey D, Enne VI, Livermore DM, Gant V, Brett SJ; INHALE WP2 Study Group. Intensivists' beliefs about rapid multiplex molecular diagnostic testing and its potential role in improving prescribing decisions and antimicrobial stewardship: a qualitative study. Antimicrob Resist Infect Control. 2021 Jun 29;10(1):95. doi: 10.1186/s13756-021-00961-4

Pandolfo AM, Horne R, Jani Y, Reader TW, Bidad N, Brealey D, Enne VI, Livermore DM, Gant V, Brett SJ; INHALE WP2 Study Group. Understanding decisions about antibiotic prescribing in ICU: an application of the Necessity Concerns Framework. BMJ Qual Saf. 2022 Mar;31(3):199-210. doi: 10.1136/bmjqs-2020-012479. Epub 2021 Jun 7. 

Qadir M, Tahseen S, McHugh TD, Hussain A, Masood F, Ahmed N, Faryal R. Profiling and identification of novel rpoB mutations in rifampicin-resistant Mycobacterium tuberculosis clinical isolates from Pakistan. J Infect Chemother. 2021 Nov;27(11):1578-1583. doi: 10.1016/j.jiac.2021.06.020. Epub 2021 Jul 7. 

Sadouki Z, McHugh TD, Aarnoutse R, Ortiz Canseco J, Darlow C, Hope W, van Ingen J, Longshaw C, Manissero D, Mead A, Pelligand L, Phee L, Readman J, Ruth MM, Standing JF, Stone N, Wey EQ, Kloprogge F. Application of the hollow fibre infection model (HFIM) in antimicrobial development: a systematic review and recommendations of reporting. J Antimicrob Chemother. 2021 Aug 12;76(9):2252-2259. doi: 10.1093/jac/dkab160

Elbadawi HS, Elhag KM, Mahgoub E, Altayb HN, Ntoumi F, Elton L, McHugh TD, Tembo J, Ippolito G, Osman AY, Zumla A, Hamid MMA. Detection and characterization of carbapenem resistant Gram-negative bacilli isolates recovered from hospitalized patients at Soba University Hospital, Sudan. BMC Microbiol. 2021 May 4;21(1):136. doi: 10.1186/s12866-021-02133-1

Elton L, Haider N, Kock R, Thomason MJ, Tembo J, Arruda LB, Ntoumi F, Zumla A, McHugh TD; And the PANDORA-ID-NET consortium. Zoonotic disease preparedness in sub-Saharan African countries. One Health Outlook. 2021;3(1):5. doi: 10.1186/s42522-021-00037-8. Epub 2021 Mar 22. 

Tweed CD, Wills GH, Crook AM, Amukoye E, Balanag V, Ban AYL, Bateson ALC, Betteridge MC, Brumskine W, Caoili J, Chaisson RE, Cevik M, Conradie F, Dawson R, Del Parigi A, Diacon A, Everitt DE, Fabiane SM, Hunt R, Ismail AI, Lalloo U, Lombard L, Louw C, Malahleha M, McHugh TD, Mendel CM, Mhimbira F, Moodliar RN, Nduba V, Nunn AJ, Sabi I, Sebe MA, Selepe RAP, Staples S, Swindells S, van Niekerk CH, Variava E, Spigelman M, Gillespie SH. A partially randomised trial of pretomanid, moxifloxacin and pyrazinamide for pulmonary TB. Int J Tuberc Lung Dis. 2021 Apr 1;25(4):305-314. doi: 10.5588/ijtld.20.0513

Chakaya J, Khan M, Ntoumi F, Aklillu E, Fatima R, Mwaba P, Kapata N, Mfinanga S, Hasnain SE, Katoto PDMC, Bulabula ANH, Sam-Agudu NA, Nachega JB, Tiberi S, McHugh TD, Abubakar I, Zumla A. Global Tuberculosis Report 2020 - Reflections on the Global TB burden, treatment and prevention efforts. Int J Infect Dis. 2021 Dec;113 Suppl 1(Suppl 1):S7-S12. doi: 10.1016/j.ijid.2021.02.107. Epub 2021 Mar 11. 

Gurusamy KS, Moher D, Loizidou M, Ahmed I, Avey MT, Barron CC, Davidson B, Dwek M, Gluud C, Jell G, Katakam K, Montroy J, McHugh TD, Osborne NJ, Ritskes-Hoitinga M, van Laarhoven K, Vollert J, Lalu M. Clinical relevance assessment of animal preclinical research (RAA) tool: development and explanation. PeerJ. 2021 Jan 27;9:e10673. doi: 10.7717/peerj.10673. 

Aklillu E, Zumla A, Habtewold A, Amogne W, Makonnen E, Yimer G, Burhenne J, Diczfalusy U. Early or deferred initiation of efavirenz during rifampicin-based TB therapy has no significant effect on CYP3A induction in TB-HIV infected patients. Br J Pharmacol. 2021 Aug;178(16):3294-3308. doi: 10.1111/bph.15309. Epub 2020 Dec 7.