We are extremely saddened by the death of Mary Price, a long-standing and popular member of our technical laboratory support team.  Mary had worked with us at the MRC Laboratory for Molecular Cell Biology at UCL since 2002 and was an exceptionally hard-working member of the team.

As eukaryotic cells divide, the nucleus must be remodelled into two distinct compartments, each encapsulating a single copy of the genome. Eukaryotes have evolved a bewildering range of strategies to achieve this - at one extreme, by disassembling the entire structure as cells begin to divide and reassembling it once division is almost complete.

Yanlan Mao has been awarded the 2021 Royal Microscopical Society Life Sciences Medal, in recognition of her contribution to our understanding of how cells and tissues are shaped and organised during the developmental process. 

In order for a cell to proliferate with fidelity, it must cycle through two non-overlapping events - replication of the genomic DNA during S phase and the segregation of the duplicated DNA into two genetically identical daughter cells during M phase. DNA replication is tightly regulated during S-phase. S-phase length is determined by DNA synthesis rate, but what controls or limits the DNA replic