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James Van Hear's picture

PhD student, Mao Lab

james.vanhear.19@ucl.ac.uk

Twitter @jimvanhear16

Research synopsis

I am interested in understanding the role of mechanical properties in colorectal cancer (CRC). Using 3D organoid culture and a number of interdisciplinary imaging, molecular and modelling techniques, I hope to understand more about the mechanical and molecular environment involved in driving CRC development, and how physiological processes like cellular extrusion and wound healing can influence cancer progression.
 

Biography

2017-2019 | Research Technician
2013-2017 | MSci, University of Birmingham
 

Funders

Medical Research Council

Research themes

Cytoskeleton
Polarity/cell shape
Signaling pathways
Cell-cell interactions
Cancer Mechanobiology
 

Technology

Light microscopy
High throughput screening
Bioinformatics
Organoid Culture