Clinical Kidney Disease
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Chronic kidney disease progresses faster in hot countries
Chronic kidney disease patients living in the hottest countries experienced an additional 8% drop in kidney function each year compared to those living in temperate climates, finds a new study.
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Celebrating research at the Royal Free London
Professor David Wheeler has been named in the internationally recognised annual Clarivate listings of the ‘world’s most influential researchers.
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Webinar: How we make real the promise of new technologies
Chris Laing joins a 2022 webinar discussing global efforts to support the implementation of technology for service change and how they can be applied in the UK.
Our Work
Our People
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Prof. David Wheeler (Head)
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Dr Ruth Pepper (Deputy Head)
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Dr Aine Burns
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![Dr Jennifer Cross](https://www.ucl.ac.uk/medicine/sites/medicine/files/styles/small_image/public/research-dialysis-profile-jenny-cross.jpg?itok=6QQe3nUV)
Jennifer Cross
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John Connolly
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Dr Sally Hamour
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Chris Laing
![Shabbir Moochhala](https://www.ucl.ac.uk/medicine/sites/medicine/files/styles/small_image/public/research-dialysis-profile-shabbir-moochhala.jpg?itok=o8hn9_Z1)
Shabbir Moochhala
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Kin Yee Shiu
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Robin Woolfson
Selected Publications
- RECOVERY Collaborative Group (inc. Ben Caplin et al.) (2022). Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. Lancet, 399 (10320), 143-151.
- Cleary F, Kim L, Wheeler D et al. (2022). Association between practice coding of chronic kidney disease (CKD) in primary care and subsequent hospitalisations and death: a cohort analysis using national audit data. BMJ Open, 12 (10).
- RECOVERY Collaborative Group (inc. Ben Caplin et al.) (2022). Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis. The Lancet, 400 (10349), 359-368.
- RECOVERY Collaborative Group (inc. Ben Caplin et al.) (2022). Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet, 399 (10325), 665-676.
- O'Callaghan-Gordo C, Arjona L, Caplin B et al. (2022). Heat stress and incidence of acute kidney injury among agricultural workers in Spain.
- Ashby DR, Caplin B, Corbett RW et al. (2022). Outcome and effect of vaccination in SARS-CoV-2 Omicron infection in hemodialysis patients: a cohort study. Nephrology Dialysis Transplantation.
- Ashby DR, Caplin B, Corbett RW et al. (2022). Severity of COVID-19 after Vaccination among Hemodialysis Patients: An Observational Cohort Study. Clin J Am Soc Nephrol.
- RECOVERY Collaborative Group (inc. Ben Caplin et al.) (2021). Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet, 397 (10274), 605-612.
- Ruiz-Alejos A, Caplin B, Miranda JJ, Pearce N, Bernabé-Ortiz A. (2021). CKD and CKDu in northern Peru: a cross-sectional analysis under the DEGREE protocol. BMC Nephrology, 22 (1), doi:10.1186/s12882-021-02239-8 (2021).
- Dritsoula A, Ponticos M, Caplin B, Wheeler DC et al. (2021). Epigenome-wide methylation profile of chronic kidney disease-derived arterial DNA uncovers novel pathways in disease-associated cardiovascular pathology. Epigenetics, 1-11.
- Hendra H, Vajgel G, Ben Caplin et al. (2021). Identifying prognostic risk factors for poor outcome following COVID-19 disease among in-centre haemodialysis patients: role of inflammation and frailty. Journal of Nephrology.
- Caplin B, Ashby D, McCafferty et al (2021). Risk of COVID-19 Disease, Dialysis Unit Attributes, and Infection Control Strategy among London In-Center Hemodialysis Patients. Clinical Journal of the American Society of Nephrology.
- RECOVERY Collaborative Group (2021). Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet, 397 (10285), 1637-1645.
- Heerspink HJL, Stefansson BV, Wheeler DC et al. for the DAPA-CKD Trial Committees and Investigators. Dapagliflozin in Patients with Chronic Kidney Disease. N Engl J Med 2020 Oct 8;383(15):1436-1446.
- Perkovic V, Jardine MJ, Wheeler DC et al; CREDENCE Trial Investigators. Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy. N Engl J Med. 2019; 380(24):2295-2306.
- Macdougall IC, White C, Wheeler DC et al; PIVOTAL Investigators and Committees. Intravenous Iron in Patients Undergoing Maintenance Hemodialysis. N Engl J Med. 2018;380(5):447-458.
- Cohen O, Rendas-Baum R, McCausland K et al. (2023). Linking changes in quality of life to haematologic response and survival in systemic immunoglobulin light-chain amyloidosis. British Journal of Haematology.
- Vergaro G, Castiglione V, Aimo A, Prontera C, Masotti S, Musetti V ... Georgiopoulos G (2023). NT-proBNP and High-Sensitivity Troponin T Hold Diagnostic Value in Cardiac Amyloidosis. European Journal of Heart Failure.
- Porcari A, Razvi Y, Masi A, Patel R, Ioannou A, Rauf MU ... Martinez-Naharro A (2023). Prevalence, Characteristics and Outcomes of Older Patients with Hereditary versus Wild-Type Transthyretin Amyloid Cardiomyopathy. European Journal of Heart Failure.
Funding and Partnerships
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