Introduction -- FASTA -- BLAST -- Modular Domain -- Multiple Sequence Alignment -- PDB -- Summary Crystal Stucture of Insulin Receptor kinase in complex with a Bisubstrate InhibitorClick here to view on RCSB PDB Phosphorylated insulin receptor tyrosine kinsae in complex with peptide substrate and ATP analogClick here to view on RCSB PDB Crystal Structure of the Tyrosine kinsae domain of the human insulin receptorClick here to view on RCSB PDB Insulin receptor showing actve and inactive conformation
Transcobalamin II protein (teal) bound to cyanobalamin (red) sittin in the extracellular region of the insulin receptor
Taken from Somwherevile For more information see full paper by T. J. Fairchild, R. P. Doyle, et al Exploring the Implications of Vitamin B12 Conjugation to Insulin on Insulin Receptor Binding |